February 4, 2021
3 Questions: Alexis Battle
Alexis Battle, associate professor of biomedical engineering, and her team have developed software that, if paired with expanded sample collection practices, could help identify more causes of genetic disorders.
January 14, 2021
Machine learning tool gives early warning of cardiac issues in COVID-19 patients
A new algorithm could warn doctors in advance of cardiac arrest or blood clots in hospitalized COVID-19 patients.
December 8, 2020
Eight from Hopkins BME earn Johns Hopkins Discovery Awards
41 multidisciplinary endeavors have been selected to receive support this year from Johns Hopkins University's Discovery Awards program. Eight of these endeavors include faculty from the Department of Biomedical Engineering.
December 7, 2020
Fighting COVID-19: Using ultraviolet light to decontaminate CT scanners
CT scans are vital to imaging lung diseases including COVID-19, but disinfecting the machines between use is time consuming. One team of researchers may have landed on a solution.
November 11, 2020
Cross-disciplinary team will design, develop devices to better treat spinal cord injuries
Funded through the Defense Advanced Research Projects Agency, the project will bring together experts from across Johns Hopkins to create solutions that work on the battlefield and on the frontlines of health care.
September 28, 2020
Johns Hopkins researchers develop system for using everyday glucose monitors to detect COVID-19 antibodies
A trio of Johns Hopkins scientists—a pharmacologist, a biomedical engineer, and a biophysicist—are pooling their knowledge to design a device that can detect whether a person has antibodies linked to SARS-CoV-2, the virus that causes COVID-19.
September 24, 2020
Septic shock starts earlier than understood and develops distinct levels of patient risk, study suggests
A new study from Johns Hopkins biomedical engineers finds that hospitals could categorize patients based on risk and develop early monitoring systems to detect early stages of septic shock.
September 10, 2020
New genetic analysis method could advance personal genomics
Geneticists could identify the causes of disorders that currently go undiagnosed if standard practices for collecting individual genetic information were expanded to capture more variants that researchers can now decipher.
August 26, 2020
Got fatigue? Study further pinpoints brain regions that may control it
Scientists at Johns Hopkins Medicine using MRI scans and computer modeling say they have further pinpointed areas of the human brain that regulate efforts to deal with fatigue.
July 10, 2020
Johns Hopkins researchers solve imaging scan problems caused by metal implants
Engineers at Johns Hopkins have solved the problem of distorted imaging scans that plague surgeons who need to use them to assess the placement of metal implants.
July 9, 2020
Scientists use nanoparticle-delivered gene therapy to inhibit blinding eye disease in rodents
In experiments in rats and mice, two Johns Hopkins scientists — an engineer and an ophthalmologist — report the successful use of nanoparticles to deliver gene therapy for blinding eye disease.
June 10, 2020
SARS-CoV-2 is mutating slowly, and that’s a good thing
Johns Hopkins scientists studying the virus that causes COVID-19 say the pathogen has few variations, a promising observation that boosts the chances of developing an effective vaccine.
May 20, 2020
Johns Hopkins team develops new method to make kidney dialysis fluid for patients with COVID-19
A team of researchers and students at Johns Hopkins are working to replenish the diminishing reserve of kidney dialysis fluid to help those with acute kidney injury, including COVID-19 patients who develop the disorder.
May 19, 2020
Researchers urge clinical trial of blood pressure drug to prevent lethal complication of COVID-19
Johns Hopkins researchers report they have identified a drug treatment that could—if given early enough—potentially reduce the risk of death from the most serious complication of COVID-19, also known as SARS-CoV-2 infection.
May 18, 2020
Johns Hopkins researchers to use machine learning to predict heart damage in COVID-19 victims
Johns Hopkins researchers recently received a $195,000 Rapid Response Research grant from the National Science Foundation to, using machine learning, identify which COVID-19 patients are at risk of adverse cardiac events such as heart failure, sustained abnormal heartbeats, heart attacks, cardiogenic shock and death.
April 17, 2020
Gene variant in noncoding DNA linked to heart failure
When scientists scour the genome for disease-causing culprits, they wouldn’t ordinarily look in so-called noncoding regions, areas of repetitive DNA that do not code for proteins. Yet, that’s exactly where Johns Hopkins scientists found genomic variations in a new study of people with heart failure.
April 17, 2020
Researchers create nanoparticle with ‘look and feel’ of red blood cells to soak up toxins
Johns Hopkins biomedical engineer Jordan Green and his colleagues have developed a nanoparticle that has the shape and “skin” of red blood cells. The red blood cell mimics can be injected into the bloodstream and circulate within vessels for long periods to absorb toxic substances.
March 6, 2020
Scientists develop free computer program to map blood flow ‘landscape’ in tumors
Johns Hopkins researchers have created a computer program for scientists at no charge that lets users readily quantify the structural and functional changes in the blood flow networks feeding tumors.
March 4, 2020
Little tissue, big mission: Beating heart tissues to ride aboard the ISS
Launching no earlier than March 6, Johns Hopkins University will send heart muscle tissues, contained in a specially-designed tissue chip the size of a small cellphone, up to the microgravity environment of the International Space Station for one month of observation.
February 26, 2020
Nanosize device ‘uncloaks’ cancer cells in mice and reveals them to the immune system
Scientists at Johns Hopkins report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals' immune systems. The new method was developed, say the researchers, to deliver an immune system "uncloaking" device directly to cancer cells.
February 25, 2020
CRISPR gene cuts may offer new way to chart human genome
In search of new ways to sequence human genomes and read critical alterations in DNA, researchers at Johns Hopkins Medicine say they have successfully used the gene cutting tool CRISPR to make cuts in DNA around lengthy tumor genes, which can be used to collect sequence information.
December 9, 2019
Little Size Holds Big Impact: Johns Hopkins Scientists Develop Nanocontainer to Ship Titan-Size Gene Therapies and Drugs Into Cells
Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size — even hefty ones attached to the gene-editing tool called CRISPR.
August 19, 2019
Personalized simulations lead to more accurate, successful treatment for common heart rhythm disorder
Natalia Trayanova and other scientists at Johns Hopkins have successfully created personalized digital replicas of the upper chambers of the heart and used them to guide the precise treatment of patients suffering from persistent irregular heartbeats. These simulations accurately identified where clinicians need to destroy tissue to restore the heart’s normal rhythm.
July 19, 2019
Test shown to improve accuracy in identifying precancerous pancreatic cysts
In a proof-of-concept study, an international scientific team led by Johns Hopkins Kimmel Cancer Center researchers has shown that a laboratory test using artificial intelligence tools has the potential to more accurately sort out which people with pancreatic cysts will go on to develop pancreatic cancers.
July 1, 2019
A snapshot in time: Study captures fleeting genetic mutations that can alter disease risk
A study examines stem cells as they differentiate into heart muscle cells, finding that small, fleeting genetic mutations can affect disease risk over time.
June 25, 2019
Drug crystals to prevent medical device fibrosis
Working with researchers at Massachusetts Institute of Technology, Joshua Doloff has devised a new way to prevent medical device fibrosis.
May 20, 2019
Brain changes linked with Alzheimer’s years before symptoms appear
In a records review of 290 people at risk for Alzheimer’s disease, scientists at Johns Hopkins say they have identified an average level of biological and anatomical brain changes linked to Alzheimer’s disease that occur three to 10 years — some even more than 30 years — before the disease’s first recognizable symptoms appear.
May 6, 2019
‘Google Maps’ for cancer: Image-based computer model reveals finer details of tumor blood flow behavior
Johns Hopkins Medicine researchers develop an image-based computer model of tumor behavior that captures more of the complexity of cancer growth.
April 25, 2019
Johns Hopkins teams up with U.C. Davis and Save the Redwoods League to sequence the first coast redwood genome
Steven Salzberg, Bloomberg Distinguished Professor of biomedical engineering at Johns Hopkins University, collaborated with researchers from the University of California, Davis and Save the Redwoods League to successfully sequence the coast redwood and giant sequoia genomes.
April 18, 2019
Scientists advance creation of ‘artificial lymph node’ to fight cancer, other diseases
In a proof-of-principle study in mice, PhD candidate John Hickey and scientists at Johns Hopkins Medicine report the creation of a specialized gel that acts like a lymph node to successfully activate and multiply cancer-fighting immune system T-cells.