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Postpartum Hemorrhage Management in the United States

2017
Team Members:
  • Larissa Chan
  • Alicia Coronado
  • Katherine Hu
  • Michael Koo
  • Maya Lapinski
  • Gavin Mischler
  • Ryan Najmi
  • Josh Punnoose
Advisors:
  • Robert Allen, PhD
  • Rachel Seay, MD

Abstract:

Every 10 minutes, a woman in the United States will face a pregnancy-related complication and a majority of these complications will result from postpartum hemorrhage (PPH). The incidence of PPH has been on the rise, occurring in 125,000 cases annually leading to a 4% increase in maternal mortality.

Defined as a blood loss of more than 500 mL after birth, PPH occurs when the uterus is too weak to contract upon its blood vessels. While non-invasive solutions provide a fertility preserving method of stopping hemorrhage, the current standard of care suffers from a 20% failure rate, forcing obstetric care providers to resort to invasive treatments. Thus obstetric care providers require a non-invasive method to establish hemostatic stability in patients with PPH, thereby reducing the use of invasive treatments.

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