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Team Members:
  • Katia Kovrizhkin
  • Sean Darcy
  • Ashley Tsang
  • Jacob Desman
  • Deborah Weidman
  • Bibhav Poudel
  • Tatiana Pereira
  • Gohta Aihara
  • Robert Liddell, MD
  • Shababa Matin
  • Harjit Singh, MD
  • Brian Holly, MD
  • Clifford Weiss, MD


A percutaneous core needle lung biopsy is a minimally invasive procedure by which a sample of abnormal lung tissue is obtained through a needle inserted directly into the targeted site of the lung using imaging guidance. The most common complication during this procedure is pneumothorax, a collapsed lung, which occurs in ~20% of all patients. With over 100,000 procedures performed in the United States alone, pneumothorax contributes to over $120 million in annual hospital costs. Thus, there is a critical need to improve the safety of percutaneous lung biopsies. The current standard of care utilizes a straight needle guided by computed tomography (CT), making it a challenge to direct the needle to the target site while navigating around critical structures, such as major blood vessels, airways, and ribs. Therefore, additional pleural punctures within a single biopsy or a repeat biopsy may be necessary to obtain an adequate sample, increasing the likelihood of pneumothorax. Our solution addresses these issues via a novel needle system equipped with the ability to access any target site in any location while minimizing the number of pleural punctures. By enabling safer high-yield lung biopsy procedures, our device has the potential to revolutionize the lung biopsy space.

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