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Justus Kebschull, PhD

Justus Kebschull
Research Interests: Brain circuit evolution, comparative connectomics & transcriptomics, viral engineering, neuro tool development
Lab Website: Kebschull Lab
Miller Research Building
Research Interests

Research Interests

Our research aims to understand the structure and function of the brain. To do so, we take a comparative approach and engineer molecular, viral, and sequencing technologies to measure neuronal connectivity networks and gene expression at scale in disease models and a wide range of vertebrates. We developed the first barcode sequencing-based approaches to map neuronal connectivity, increasing throughput of single-neuron mapping by orders of magnitude and opening the door to single-cell comparative connectomics. We complement these barcoding approaches by in situ sequencing of barcodes and genes. Leveraging these technologies, we ask questions including: How do new brain regions and connections evolve to support new computations? What are the organizing principles and fundamental circuit motifs of the vertebrate brain? And how do drugs of abuse and neurodevelopmental disorders break these principles? Our work is highly interdisciplinary, residing at the interface of molecular engineering, neuroscience, synthetic and evolutionary biology, genomics, virology, and computational biology.

Titles & Affiliations


  • Assistant Professor, Biomedical Engineering


  • Post-doctoral fellowship, Neuroscience, Stanford University, 2017-2020
  • PhD, Neuroscience, Cold Spring Harbor Laboratory, 2017
  • MSci, Systems Biology, University of Cambridge, 2011
  • BA, Natural Sciences, University of Cambridge, 2011
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