Dr. Green’s Biomaterials and Drug Delivery Laboratory is interested in biomaterials, drug delivery, gene therapy, nanobiotechnology, and cell engineering. Research findings — and the technologies developed — are applied in the fields of ophthalmology, oncology, and regenerative medicine.
The lab works within the chemistry/biology/engineering interface to answer fundamental scientific questions, and to create innovative technologies and therapeutics that can directly benefit human health.
Current projects include:
- Development of safe and effective biodegradable nanoparticles for DNA and siRNA delivery to treat cancer
- Polymeric microparticle-based biological treatments for age-related macular degeneration
- Design of biomimetic artificial antigen presenting cells for immunoengineering
- Enabling technologies for tissue engineering and regenerative medicine
- Professor, Biomedical Engineering
- Director, Biomedical Engineering Undergraduate Program
- Professor, Ophthalmology
- Professor, Oncology
- Professor, Neurosurgery
- Professor, Materials Science & Engineering
- Professor, Chemical & Biomolecular Engineering
Affiliated Centers & Institutes
- PhD, Biological Engineering, Massachusetts Institute of Technology, 2007
- BS, Chemical Engineering, Biomedical Engineering, Carnegie Mellon University, 2003
April 17, 2020Johns Hopkins biomedical engineer Jordan Green and his colleagues have developed a nanoparticle that has the shape and “skin” of red blood cells. The red blood cell mimics can be injected into the bloodstream and circulate within vessels for long periods to absorb toxic substances.
February 26, 2020Scientists at Johns Hopkins report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals' immune systems. The new method was developed, say the researchers, to deliver an immune system "uncloaking" device directly to cancer cells.
December 9, 2019Little Size Holds Big Impact: Johns Hopkins Scientists Develop Nanocontainer to Ship Titan-Size Gene Therapies and Drugs Into CellsScientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size — even hefty ones attached to the gene-editing tool called CRISPR.