Congrats to PhD Student Jessica Stelzel for our new News & Views article out in Nature Materials: CHECK IT OUT!
Other News: pending soon.
We are honored to be a part of a large Johns Hopkins School of Medicine team that recently received a DARPA award for investigating ultrasound/Doppler implant systems for spinal cord injury and repair! (Continue reading just below)
Cross-disciplinary team will design, develop devices to better treat spinal cord injuries
Funded through the Defense Advanced Research Projects Agency, the project will bring together experts from across Johns Hopkins to create solutions that work on the battlefield and on the frontlines of health care.
A team of Johns Hopkins biomedical engineers and neurosurgeons has received $13.48 million from the Defense Advanced Research Projects Agency to develop implantable ultrasound and other devices that could revolutionize care for people suffering from spinal cord injuries. The results could benefit thousands of U.S. service members and civilians who sustain spinal cord injuries every year…. CONTINUE READING
Drug crystals to prevent medical device fibrosis
Crystallized drug prevents immune system rejection of transplanted pancreatic islet cells.
Implanted medical devices can save lives, but can also put patients at the risk of fibrosis, a condition in which the immune system attacks the device and produces scar tissue around it, interfering with the device’s functionality. Working with researchers at Massachusetts Institute of Technology, Joshua Doloff, an assistant professor of biomedical engineering at Johns Hopkins University and former MIT postdoc, has devised a new way to prevent fibrosis: loading implantable devices with a crystallized immunosuppressant drug…. CONTINUE READING
Faculty Highlight: Meet Joshua Doloff, Assistant Professor of BME
Joshua Doloff joined the Johns Hopkins Department of Biomedical Engineering as an assistant professor in November 2018. In this interview, Doloff, who has an interest in technology and biology, describes his eagerness to build research collaborations and provide mentorship to students. He also discusses his “eureka moments,” the research he plans to conduct at Hopkins, and the future of engineering…. CONTINUE READING
Oxygen-tracking method could improve diabetes treatment
Measurements could help scientists develop better designs for a bioartificial pancreas.
Transplanting pancreatic islet cells into patients with diabetes is a promising alternative to the daily insulin injections that many of these patients now require. These cells could act as a bioartificial pancreas, monitoring blood glucose levels and secreting insulin when needed…. CONTINUE READING
Study points a way to better implants
Selectively blocking immune cells can prevent formation of scar tissue around medical devices.
Medical devices implanted in the body for drug delivery, sensing, or tissue regeneration usually come under fire from the host’s immune system. Defense cells work to isolate material they consider foreign to the body, building up a wall of dense scar tissue around the devices, which eventually become unable to perform their functions… CONTINUE READING
Scientists have figured out how to stop our bodies from fighting electronic implants
Scar tissue may no longer be an obstacle on our road to becoming cyborgs
We may dream of one day becoming cyborgs, with RFID chips implanted in our hands or bionic eyes, but the human body won’t necessarily cooperate. Implantable devices like pacemakers have been used regularly for decades, but they often encounter a build-up of scar tissue, or fibrotic tissue around the implants that can hinder functionality. Now, biologists have figured out a way to fight that process without seriously compromising the entire immune system…. CONTINUE READING
Designing better medical implants
Optimal size and shape allow implantable devices to last longer in the body.
Biomedical devices that can be implanted in the body for drug delivery, tissue engineering, or sensing can help improve treatment for many diseases. However, such devices are often susceptible to attack by the immune system, which can render them useless.
A team of MIT researchers has come up with a way to reduce that immune-system rejection. In a study in Nature Materials, they found that the geometry of implantable devices has a significant impact on how well the body will tolerate them… CONTINUE READING