Publications

For a full overview visit:

Nature Materials, August 2019
Nature Materials, June 2017
Nature Medicine, March 2016
Nature Materials, June 2015

Selected Publications

  1. Doloff JC*^, Veiseh O*^, de Mezerville R^, Sforza M, Perry TA, Haupt J, Jamiel M, Chambers C, Nash A, Aghlara-Fotovat S, Stelzel JL, Bauer SJ, Neshat SY, Hancock J, Romero NA, Hidalgo YE, Leiva IM, Munhoz AM, Bayat A, Kinney BM, Hodges HC, Miranda RN, Clemens MW, & Langer R^. 2021. The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits and humansNat Biomed Eng. June 21; https://doi.org/10.1038/s41551-021-00739-4 (*: co-first, ^: co-corresponding).
  2. Stelzel J and Doloff JC. 2021. MAP-ing a way towards tissue repair. Nature Materials. Mar 26;(20):452–453. doi: 10.1038/s41563-021-00963-y.
  3. Mao L, Li L, Huang Y, Delcassian D, Chahal J, Han J, Shi Y, Sadtler K, Lin J, Doloff JC, Langer RS, and Anderson DG. 2019. Rapid combinatorial development of heterocyclic lipidoids for mRNA vaccine delivery and STING-mediated immune cell activation. Nature Biotechnology. Sep 30. doi: 10.1038/s41587-019-0247-3.
  4. Farah S*, Doloff JC*, Mueller P, Sadraei A, Han HJ, Olafson K, Tyas K, Tam HH, Hollister-Locke J, Kowalski PS, Griffin M, Meng A, McAvoy M, Graham AC, McGarrigle J, Greiner DL, Weir G, Oberholzer J, Langer R, and Anderson DG. 2019. Long-Term Implant Fibrosis Prevention in Rodents and Non-Human Primates Using Crystallized Drug FormulationsNature Materials. Aug;18(8):892-904. doi: 10.1038/s41563-019-0377-5.
  5. Spanoudaki V, Doloff JC, Huang W, Norcross SR, Farah S, Langer R, and Anderson DG. 2019. Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning. PNAS. Feb 26. doi: 10.1073/pnas.1815909116.
  6. Bochenek MA, Veiseh O, Vegas AJ, McGarrigle JJ, Qi M, Marchese E, Omami M, Doloff JC, Mendoza-Elias J, Nourmohammadzadeh M, Khan A, Yeh C, Isa D, Ghani S, Li J, Landry C, Bader AR, Olejnik K, Chen M, Hollister-Lock J, Wang Y, Greiner DL, Weir GC, Strand BL, Rokstad AM, Lacik I, Langer R, Anderson DG, and Oberholzer J. 2018. Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaquesNature Biomedical Engineering. Aug 13. doi: 10.1038/s41551-018-0275-1.
  7. Xie X*, Doloff JC*, Yesilyurt V*, Sadraei A*, McGarrigle J, Omami M, Veiseh O, Isa D, Ghani S, Joshi I, Li J, Wang W, Tam HH, Tao J, Chen H, Yang B, Oberholzer J, Langer RS, Anderson DG. 2018. Reduction of measurement noise in a continuous glucose monitor by coating the sensor with a zwitterionic polymerNature Biomedical Engineering. July 30. doi: 10.1038/s41551-018-0273-3.
  8. Khan OF, Kowalski P*, Doloff JC*, Tsosie JK, Bakthavatchalu V, Bodi CW, Haupt J, Jamiel M, Langer R, and Anderson DG. 2018. Targeted gene knockdown in the vasculature of nonhuman primates using optimized low molecular weight polyethylenimine-based amphiphiles. Science Advances. Jun 27;4(6):eaar8409. doi: 10.1126/sciadv.aar8409.
  9. Doloff JC, Veiseh O, Vegas AJ, Tam HH, Farah S, Ma M, Li J, Bader A, Chiu A, Sadraei A, Aresta-Dasilva S, Griffin M, Jhunjhunwala S, Webber M, Siebert S, Tang K, Chen M, Langan E, Dholokia, Thakrar R, Qi M, Oberholzer J, Greiner DL, Langer R, and Anderson DG. 2017. Colony Stimulating Factor-1 Receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primatesNature Materials. Mar 20. doi: 10.1038/nmat4866.
  10. Vegas AJ, Veiseh O, Doloff JC, Ma M, Tam HH, Bratlie K, Li J, Bader A, Langan E, Olejnik K, Fenton P, Kang JW, Hollister-Locke J, Bochenek MA, Chiu A, Siebert S, Tang K, Jhunjhunwala S, Aresta-Dasilva S, Dholokia N, Thakrar R, Vietti T, Cohen J, Siniakowicz K, Qi M, Lyle S, Harlan DM, Greiner DL, Oberholzer J, Weir GC, Langer RS, and Anderson DG. 2016. Combinatorial development of hydrogels that mitigate the foreign body response in primatesNature Biotechnology. Mar;34(3):345-52. doi:10.1038/nbt.3462.
  11. Vegas AJ, Veiseh O, Gurtler M, Millman J, Paglicua F, Bader A, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, Greiner DL, Weir GC, Melton DA, Langer R, and Anderson DG. 2016. Long term glycemic control using polymer encapsulated, human stem cell derived b-cells in immune competent rodents. Nature Medicine. Mar;22(3):306-11. doi:10.1038/nm.4030.
  12. Veiseh O*, Doloff JC*, Ma M*, Vegas AJ, Tam HH, Bader AR, Li J, Langan E, Wyckoff J, Loo WS, Jhunjhunwala S, Chiu A, Siebert S, Tang K, Hollister-Locke J, Aresta-Dasilva S, Bochenek M, Mendoza-Elisa J, Wang Y, Qi M, Lavin D, Chen M, Dholokia N, Thakrar R, Lacik I, Weir GC, Oberholzer J, Greiner DL, Langer R, and Anderson DG. 2015. Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primatesNature Materials, Jun; 14(6):643-51.
  13. Doloff JC*, Chen CS*, and Waxman DJ. 2014. Anti-tumor innate immunity activated by metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2Molecular Cancer, Jun 26; 13(1): 158.
  14. Chen CS*, Doloff JC*, and Waxman DJ. 2014. Intermittent metronomic drug schedule is essential for activating anti-tumor innate immunity and tumor xenograft regression.  Neoplasia, Jan; 16(1): 84-96.
  15. Doloff JC and Waxman DJ. 2012. VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regressionCancer Research, Mar 1; 72(5): 1103-15.