News & Events

Research highlights

October 23, 2014

The Yin and Yang of calmodulin revealed by a biological signal generator

Researchers in the Calcium Signals Laboratory have discovered a mechanism that governs a cellular dialog between the two forms of calmodulin. This enables new strategies for treating diseases relating to maladaptive bioelectrical and Ca2+ signaling, such as cardiac arrhythmias, epilepsy, and Parkinson’s Disease.

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September 2, 2014

Johns Hopkins researchers discover that an FDA-approved HIV drug may be useful in treating breast cancer metastasis

Use of drugs previously approved for other diseases, such as HIV and rheumatoid arthritis, opens attractive possibilities for treating cancer patients — as repurposed or repositioned drugs promises significant savings in development time and resources.

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August 26, 2014

Error memories enable improved performance and faster learning

A study reveals that the brain controls how much it is willing to learn from the current error based on a previously unknown form of memory: a memory of errors.

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July 31, 2014

Zooming in and out of the mouse brain

The researchers’ new “map” of the mouse auditory cortex could ultimately lead to better ways of treating people with hearing loss.

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July 24, 2014

Database of Pediatric MR Images Aids Diagnosis, Treatment

By building a “cloud database” of MR images collected from children with normal and abnormal brains, researchers aim to give physicians access to a Google-like search system that will improve the way pediatric brain disorders are diagnosed and treated.

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June 19, 2014

All in the family — sodium and calcium ion channels share common roots

Novel treatment strategies for arrhythmias, myotonias, and neurodegeneration provided by an ancient feedback module commonly shared between voltage-gated sodium and calcium channels.

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Trayanova

May 22, 2014

Improving cardiac ablation treatment with virtual heart mapping

Dr. Trayanova and team are exploring whether the patient’s virtual heart could be used to noninvasively determine the optimal ablation targets with a lot more accurately.

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May 21, 2014

I-STAR Lab refines ultra-low dose CT scans

Armed with pragmatism and advanced computer modelling techniques, BME researchers have made strides in improving CT image quality while reducing X-ray exposure and other negative consequences of the scanning technique.

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May 12, 2014

Solving the paradox: How one bad apple spoils the pie of cardiac rhythms

BME and neuroscience researchers exploit live-cell biochemistry, electrophysiology, and mathematical simulations to solve how calmodulinopathies can lead to life-threatening cardiac arrhythmogenic events.

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February 27, 2014

Engineering safer surgery: The LevelCheck algorithm translated to first clinical studies

Advanced 3D-2D image registration leverages high-speed computing to provide surgeons with an on-demand, labeled visual depiction of the spine and surgical target in the operating room.

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