News & Events

Research highlights

February 25, 2020

CRISPR gene cuts may offer new way to chart human genome

In search of new ways to sequence human genomes and read critical alterations in DNA, researchers at Johns Hopkins Medicine say they have successfully used the gene cutting tool CRISPR to make cuts in DNA around lengthy tumor genes, which can be used to collect sequence information.

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The image shows green and blue blobs from under a microscope.

December 9, 2019

Little Size Holds Big Impact: Johns Hopkins Scientists Develop Nanocontainer to Ship Titan-Size Gene Therapies and Drugs Into Cells

Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size — even hefty ones attached to the gene-editing tool called CRISPR.

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Personalized simulations can lead to better treatment for common heart rhythm disorder.

August 19, 2019

Personalized simulations lead to more accurate, successful treatment for common heart rhythm disorder

Natalia Trayanova and other scientists at Johns Hopkins have successfully created personalized digital replicas of the upper chambers of the heart and used them to guide the precise treatment of patients suffering from persistent irregular heartbeats. These simulations accurately identified where clinicians need to destroy tissue to restore the heart’s normal rhythm.

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CT image of pancreatic cyst

July 19, 2019

Test shown to improve accuracy in identifying precancerous pancreatic cysts

In a proof-of-concept study, an international scientific team led by Johns Hopkins Kimmel Cancer Center researchers has shown that a laboratory test using artificial intelligence tools has the potential to more accurately sort out which people with pancreatic cysts will go on to develop pancreatic cancers.

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July 1, 2019

A snapshot in time: Study captures fleeting genetic mutations that can alter disease risk

A study examines stem cells as they differentiate into heart muscle cells, finding that small, fleeting genetic mutations can affect disease risk over time.

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June 25, 2019

Drug crystals to prevent medical device fibrosis

Working with researchers at Massachusetts Institute of Technology, Joshua Doloff has devised a new way to prevent medical device fibrosis.

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Brain Changes Linked With Alzheimer’s Years Before Symptoms Appear

May 20, 2019

Brain changes linked with Alzheimer’s years before symptoms appear

In a records review of 290 people at risk for Alzheimer’s disease, scientists at Johns Hopkins say they have identified an average level of biological and anatomical brain changes linked to Alzheimer’s disease that occur three to 10 years — some even more than 30 years — before the disease’s first recognizable symptoms appear.

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Maps of tumors grown in mice.

May 6, 2019

‘Google Maps’ for cancer: Image-based computer model reveals finer details of tumor blood flow behavior

Johns Hopkins Medicine researchers develop an image-based computer model of tumor behavior that captures more of the complexity of cancer growth.

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Sequenced genome sizes

April 25, 2019

Johns Hopkins teams up with U.C. Davis and Save the Redwoods League to sequence the first coast redwood genome

Steven Salzberg, Bloomberg Distinguished Professor of biomedical engineering at Johns Hopkins University, collaborated with researchers from the University of California, Davis and Save the Redwoods League to successfully sequence the coast redwood and giant sequoia genomes.

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T-cells interacting with the transparent gel.

April 18, 2019

Scientists advance creation of ‘artificial lymph node’ to fight cancer, other diseases

In a proof-of-principle study in mice, PhD candidate John Hickey and scientists at Johns Hopkins Medicine report the creation of a specialized gel that acts like a lymph node to successfully activate and multiply cancer-fighting immune system T-cells.

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