Translational Cell & Tissue Engineering Focus Area Curriculum Requirements

students in lab


Translational Cell & Tissue Engineering develops and translates advanced technologies to enhance or restore function at the molecular, cellular, and tissue levels. In recent years, TCTE has focused on understanding and harnessing the power of stem cells in concert with developing new biomaterials to guide cell behavior and reconstruct tissues and organs ranging from bone, cartilage, liver, pancreas, skin, blood vessel, and peripheral nerve. To complement these efforts, which are designed to meet critical healthcare needs, Hopkins BME researchers are leaders in approaches to not only augment regeneration, but also to treat complex disease such as cancer, diabetes, arthritis, and neurological disorders such as Parkinson’s and Alzheimer’s disease. This focus area provides students opportunities to work with faculty who specialize in areas that include biomaterials, bioreactors, gene and drug delivery, immunoengineering, regenerative medicine, and stem cell engineering. Student can also participate in research in the Translational Tissue Engineering Center and any other relevant Johns Hopkins research center.

Below, you will find a suggested list of courses to help you in your course planning. Students are expected to complete at least two of the core focus area courses. Your academic interests determine the remaining courses (focus area electives). You will meet with the faculty lead of your chosen focus area to determine your course plan. The program administrator will provide additional advisement and course approval. Please note that all listed courses are suggested and may not always be offered. Course offerings are subject to change from semester to semester.

All TC&TE track students* are expected to complete the following four courses, which constitute the core curriculum for this focus area:
  • Advanced Cell and Tissue Engineering Lab (EN.580.751/4)
  • Advanced Topics in Regenerative and Immune Engineering (EN.580.752)
  • Cellular Engineering (EN.580.641)
  • Tissue Engineering (EN.580.642)
*If you are a Johns Hopkins undergraduate who has already taken these courses, consult with your faculty advisor to select alternative courses.
TC&TE track students will generally complete 3 to 5 of the following electives as needed to reach the 30 credits required for graduation (note that two options are to earn up to 6 research-based credits or select alternative electives of your own choosing, as described below):
  • Advanced Orthopaedic Tissue Engineering (EN.580.643)
  • Biomedical Applications of Glycoengineering (EN.580.644)
  • Chemical Biology I (AS.030.619)
  • Chemical Biology II (AS.030.620)
  • Computational Stem Cell Biology (EN.580.647)
  • Engineering Principles of Drug Delivery (EN.540.665)
  • Fundamentals of Physics and Chemistry in Nanomaterials (EN.670.619)
  • Introduction to the Brain (AS.020.612)
  • Metabolic Systems Biotechnology (EN.540.602)
  • Molecular Engineering (EN.580.646)
  • Physics of Cell Biology: From Mechanics to Information (AS.250.648)
  • Physical Chemistry of Biological Macromolecules (AS.250.689)
  • Physical Epigenetics (EN.580.446)
  • Polymer Chemistry & Biology (EN.510.606)
  • Systems Pharmacology and Personalized Medicine (EN.580.640)
Students will select science, technology, engineering, or math courses to complete 30 credit hours (note that all courses required for graduation can be from the TC&TE focus area, but do not need to be). Ideally the electives will complement the focus track curriculum but can include any appropriate Johns Hopkins courses (to be selected in consultation with a student’s academic advisor). NOTE: Up to 6 units of research-based credit can apply to the Additional Electives category. To obtain credit for research, enroll in any of the following courses:
  • Applied Research and Grant Methodology I and II (EN.580.821/822)
  • BME MSE Research Practicum (EN.580.850) – spring semester only
  • Research in Biomedical Engineering (EN.580.801/802)