Regenerative and Immune Engineering Focus Area Curriculum Requirements












Regenerative and Immune Engineering has traditionally focused on understanding and harnessing the power of stem cells in concert with developing new biomaterials to guide cell behavior and reconstruct tissues and organs ranging from bone, cartilage, liver, pancreas, skin, blood vessel, and peripheral nerve. To complement these efforts designed to meet critical health care needs, Hopkins’ researchers are leaders in immunoengineering approaches to not only augment regeneration, but also to treat diseases such as cancer. This focus area provides students to work with faculty who specialize in areas that include biomaterials, bioreactors, gene and drug delivery, immunoengineering, regenerative medicine, and stem cell engineering and participate in the Translational Tissue Engineering Center.

In the Regenerative and Immune Engineering focus area students are expected to complete at least two of the following courses. This is a sample course listing:
  • Advanced Orthopaedic Tissue Engineering (EN.580.643/4)
  • Biomedical Applications of Glycoengineering (EN.580.644)
  • Cellular Engineering (EN.580.641)
  • Computational Stem Cell Biology (to be offered Spring 2018)
  • Physical Epigenetics (EN.580.446)
  • Tissue Engineering (EN.580.642)
Regenerative and Immune Engineering focus area students are expected to take ≥ 5 focus area courses in total, which can also include. This is a sample course listing:
  • Animation in Nanotechnology & Medicine (EN.670.697)
  • Application of Molecular Evolution to Biotechnology (EN.540.637)
  • Biochemical Sensors (585.610; offered online)
  • Biological Fluid and Solid Mechanics (585.618; offered online)
  • Biomaterials (585.608; offered online)
  • Biomaterials II: Host response and biomaterials applications (EN510.607)
  • Biomolecular Materials I – Soluble Proteins and Ampiphiles (EN.510.621)
  • Biosensor Materials and Mechanisms (EN.510.637)
  • Cell and Tissue Engineering (585.629; offered online, credit will not be awarded for this course and 580.641/2)
  • Cell Mechanics (585.609; offered online)
  • Colloids and Nanoparticles (EN.540.603)
  • Computational Protein Structure Prediction and Design (EN.540.614)
  • Design of Biomolecular Systems (EN.540.605)
  • Epigenetics and Chromosomal Dynamics (AS.020.640)
  • Ethics of Biomedical Engineering Innovation (EN.580.415)
  • Fundamental Physics and Chemistry of Nanomaterials (EN.670.619)
  • Interfacial Science with Applications to Nanoscale Systems (EN.540.615)
  • Introduction to Polymeric Materials (EN.540.622)
  • Introduction to Rehabilitation Engineering (EN.580.656)
  • Mechanical Properties of Biomaterials (EN.510.635)
  • Metabolic Systems Biotechnology (EN.540.602)
  • Microfabrication Laboratory (EN.580.595)
  • Micro/Nanotechnology: The Science and Engineering of Small Structures (EN.540.640)
  • Physical Chemistry of Biological Macromolecules (AS.250.689)
  • Polymer Chemistry & Biology (EN.510.606)
  • Polymer Design and Bioconjugation (EN.540.662)
  • Polymer Physics (EN.540.660)
  • Simulation of Biomolecules and Membranes (EN.510.634)
  • Stem Cells (AS.020.620)
  • Supramolecular Materials and Nanomedicine (EN.540.628)
  • Systems Pharmacology and Personalized Medicine (EN.580.640)
Students will select science, technology, engineering, or math courses to complete a total of 30 credits (note that courses required for graduation can be from the Regenerative and Immune Engineering focus area); ideally the electives will complement focus track courses but can include any appropriate Johns Hopkins courses provided that > 5 courses [overall] are qualifying BME courses. (Qualifying BME courses have “580” or “585” as their first three numerical digits (i.e., or First year, non-thesis track students who are potentially interested in completing a thesis are encouraged to consider taking the Applied Research & Grant Methodology course sequence.