People
Yanan Du

Yanan Du, PhD

Associate Professor, Tsinghua University

Office: Medical Sciences Building, Room B310
+86-10-62781691
duyanan@tsinghua.edu.cn


Education

PhD, Bioengineering, National University of Singapore (2007)
BE, Chemical Engineering, Tsinghua University (2002)

Research Interests

We are working in the field of microtissue engineering, a unique and new research area, which integrates conventional tissue engineering, biomaterials and microfabrication technologies to engineer microscale 3D tissues or microenvironments recapitulating the physiological and architectural features of native tissue niche with well-defined precision and bio-mimicry. Microtissue engineering provides innovative and effective tools and solutions for cell/tissue engineering, regenerative medicine, drug screening and pathology study. We are working in highly inter-disciplinary and innovation-driven arena, providing unlimited opportunities for creative and ambitious minds. Some of our dreams include building functional liver/heart/cartilage tissues; achieving better regenerative therapy to cure cardiovascular/liver diseases; discovering anti-fibrotic compound to treat liver or heart diseases.

Publications

Liu L, You Z, Yu H, Zhou L, Zhao H, Yan X, Li D, Wang B, Zhu L, Xu Y, Xia T, Shi Y, Huang C, Hou W, Du Y*, ‘Mechanotransduction-modulated fibrotic microniches reveal the contribution of angiogenesis in liver fibrosis’ Nature Materials 16(12):1252-1261(2017)

Jiang S, Li SC, Huang C, Chan BP, Du Y*. Physical Properties of Implanted Porous Bioscaffolds Regulate Skin Repair: Focusing on Mechanical and Structural Features Adv Healthc Mater. 2018 Jan 15. doi: 10.1002/adhm.201700894

Qi C, Li Y, Badger P, Yu H, You Z, Yan X, Liu W, Shi Y, Xia T, Dong J, Huang C, Du Y*, ‘Pathology-targeted cell delivery via injectable micro-scaffold capsule mediated by endogenous TGase’ Biomaterials 126:1-9 (2017)

Zhu L, Fan X, Wang B, Liu L, Yan X, Zhou L, Zeng Y, Poznansky MC, Wang L, Chen H, Du Y* ‘Biomechanically primed liver microtumor array as a high-throughput mechanopharmacological screening platform for stroma-reprogrammed combinatorial therapy’ Biomaterials 124:12-24 (2017)

Fan X, Zhu L, Wang K, Wang B, Wu Y, Xie W, Huang C, Chan BP, Du Y* ‘Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory’ Adv Healthc Mater. doi: 10.1002/adhm.201601152. (2017)