Amir Manbachi, PhD
Assistant Research Professor
Associate Director of the BME Undergraduate Design ProgramAssociate Faculty, Armstrong Institute for Patient Safety and Quality
Office: Clark 208F
Postdoctoral Scholar, Harvard-MIT Division of Health Sciences and Technology, 2016
PhD, Biomedical Engineering, University of Toronto, Canada, 2015
MASc, Biomedical Engineering, University of Toronto, Canada, 2010
BASc, Engineering Science, University of Toronto, Canada, 2008
Dr. Manbachi is a faculty member of the Center for Bioengineering Innovation and Design within the Department of Biomedical Engineering, Johns Hopkins University. His interests include research and education in image-guided interventions, including medical device development, x-ray and ultrasound imaging techniques, and therapeutic ultrasound. His work includes mentorship with BME Design Teams as well as close collaboration with clinical experts in Surgery and Radiology at Johns Hopkins.
His previous work included development of ultrasound-guided spine surgery. He obtained his PhD from the University of Toronto, under the supervision of Dr. Richard S.C. Cobbold. Prior to joining Johns Hopkins, he was a postdoctoral fellow at Harvard-MIT Division of Health Sciences and Technology (2015-16) and the founder and CEO of Spinesonics Medical (2012–2015), a spinoff from his doctoral studies.
Amir is an author on ~ 20 peer-reviewed journal articles, 5 patent / disclosure applications and a book entitled “Towards Ultrasound-guided Spinal Fusion Surgery.” His interdisciplinary research has been recognized by a number of awards, including University of Toronto’s 2015 Inventor of year award, and Ontario Brain Institute 2013 fellowship. Dr. Manbachi has extensive teaching experience, particularly in the field of medical imaging and entrepreneurship both at Hopkins and Toronto, for which he received the University of Toronto’s Teaching Excellence award in 2014.
Manbachi A, De Silva T, Uneri A, Jacobson M, Goerres J, Ketcha M, Han R, Aygun N, Thompson D, Ye X, Vogt S, Kleinszig G, Molina C, Garzon-Muvdi T, Raber MR, Groves M, Wolinsky JP, Siewerdsen JH. “Clinical Translation of the LevelCheck Algorithm for Automatic Localization of Target Vertebrae in Spine Surgery”. Ann Biomed Eng (2018). https://doi.org/10.1007/s10439-018-2099-2
Brown AJV, Uneri A, De Silva TS, Manbachi A, Siewerdsen JH. “Design and validation of an open-source library of dynamic reference frames for research and education in optical tracking,” J. Med. Imag. 5(2) 021215 (9 February 2018)
Manbachi A, Kreamer-Tonin K, Walch P, Khoshakhlagh P, Zhang YS, Montague C, Acharya S, Logsdon EA, Allen RA, Durr NJ, Luciano MG, Theodore N, Brem H, Yazdi Y “Starting A Medical Technology Venture as an Young Academic Innovator or Student Entrepreneur” Ann Biomed Eng (2018) 46: 1.
Manbachi A, De Silva T, Uneri A, Jacobson M, Goerres J, Ketcha M, Han R, Aygun N, Thompson D, Ye X, Vogt S, Kleinszig G, Molina C, Garzon-Muvdi T, Raber MR, Groves M, Wolinsky JP, Siewerdsen JH. “Clinical Translation of the LevelCheck Algorithm for Automatic Localization of Target Vertebrae in Spine Surgery”. Presented at the “North American Spine Society” 2017 Annual Meeting, Orlando, Florida, USA.
Zhang X, Ellens NPK, Belzberg M, Miller P, Cohen AR, Brem H, Siewerdsen JH, Manbachi A. “Design of a Low-power, Minimally Invasive High Intensity Focused Ultrasound Device for Ablative Applications in Neuro-Oncology: A Simulation Study” Presented at the 59th AAPM (American Association of Physicists in Medicine) Annual Meeting & Exhibition (Denver, CO, 2017), abstract #37878.
Manbachi A. “Towards Ultrasound-guided Spinal Fusion Surgery” Springer Theses, Springer International Publishing (2016) ISBN 978-3-319-29832–0.
Manbachi A, Cobbold RSC, Ginsberg HJ, “Guided Pedicle Screw Insertion: Techniques and Training” Spine J. 2014; 14(1): 165–79.
Gdyczynski C, Manbachi A, Hashemi M, Lashkari B, Cobbold RSC, “On Estimating the directionality distribution in pedicle trabecular bone from micro-CT images” Physiol. Meas. 2014; 35(12): 2415–2428.
Manbachi A, Lee M, Foster FS, Ginsberg HJ, Cobbold RSC. “Design and fabrication of a low-frequency (1-3 MHz) ultrasound transducer for accurate placement of screw implants in the spine” Proc. SPIE 9040, Medical Imaging 2014: Ultrasonic Imaging and Tomography, 90400H (March 20, 2014); doi:10.1117/12.2042965.
Lashkari B, Manbachi A, Mandelis A, Cobbold RSC, “Slow and Fast Ultrasonic Wave separation improvement in human trabecular bones using Golay code modulation” JASA. 2012; 132(3), EL222–8.
Manbachi A, Cobbold RSC, “Development and Application of Piezoelectric Materials for Ultrasound Generation and Detection” Ultrasound 2011; 19(4): 187–196.
Manbachi A, Hoi Y, Wasserman BA, Lakatta EG, Steinman DA “On the Shape of the Common Carotid Artery, with Implications for Blood Velocity Profiles” Physiol Meas 2011; 32(12): 1885–97.
Manbachi A, Shrivastava S, Cioffi M, Chung BG, Moretti M, Demirci U, Yliperttula M, Khademhosseini A “Microcirculation within grooved substrates regulates cell positioning and cell docking inside microfluidic channels” Lab Chip. 2008; 8(5): 747–54.