People

JHU biomedical engineering primary faculty

Rachel  Karchin, PhD

Rachel Karchin, PhD

Associate Professor
The William R. Brody Faculty Scholar
Institute for Computational Medicine

Office: Hackerman Hall 217A
Lab: Karchin Lab
(410) 516-5578
karchin@jhu.edu

Education

Ph.D., Computer Science, University of California, Santa Cruz, 2003
M.S., Computer Science, University of California, Santa Cruz, 2000
B.S., Computer Engineering, University of California, Santa Cruz, 1998

Research Interests

Genetic variation is critical to our susceptibility to diseases and response to medications. Yet the functional consequences of most genetic variants are unknown. We are working to predict these consequences using computation, by integrating information from molecular modeling and sequence analysis with clinical patient data and in vitro functional studies, through collaborations with physicians, genetic counselors, and experimental biologists. We are particularly interested in inherited cancer susceptibilities and gain of function mutations in tumor genomes.

Publications Search

From Pub Med   |   Google Scholar Profile