JHU biomedical engineering primary faculty
Rachel Karchin, Ph.D.
The William R. Brody Faculty Scholar
Institute for Computational Medicine
Office: Hackerman Hall 217A
Lab: Karchin Lab
Ph.D., Computer Science, University of California, Santa Cruz, 2003
M.S., Computer Science, University of California, Santa Cruz, 2000
B.S., Computer Engineering, University of California, Santa Cruz, 1998
Genetic variation is critical to our susceptibility to diseases and response to medications. Yet the functional consequences of most genetic variants are unknown. We are working to predict these consequences using computation, by integrating information from molecular modeling and sequence analysis with clinical patient data and in vitro functional studies, through collaborations with physicians, genetic counselors, and experimental biologists. We are particularly interested in inherited cancer susceptibilities and gain of function mutations in tumor genomes.
From Pub Med | Google Scholar Profile