JHU biomedical engineering faculty
Xiaofeng Jia, M.D., Ph.D.
Assistant Research Professor
Department of Biomedical Engineering
Office: Traylor 710B
MD, Clinical Medicine, Zhengjiang Medical University, 1994
MS, Surgery, Shanghai Medical University, 1997
PhD, Surgery (Orthopaedics), Fudan University, 2003
Post-doctoral training, Biomedical Engineering, Johns Hopkins University, 2004-2007
Brain Monitoring and Therapeutic Hypothermia
We focus on the development of novel translational tools for uncovering mechanisms of brain injury after cardiac arrest, monitoring and tracking the neurological injuries, and optimizing treatments like therapeutic hypothermia.
Peripheral Nerve Injury
We aim to develop novel methodology to promote nerve regeneration for peripheral nerve injury and developing novel nerve scaffold for the next generation of nerve signal controlled prosthetic limbs.
Jia X, Koenig MA, Zhang X, Zhang J, Chen T, Chen Z. Residual Motor Signal In Long-Term Human Severed Peripheral Nerves And Feasibility Of Neural Signal-Controlled Artificial Limb. The Journal of Hand Surgery (AM). 2007 May–June, 32(5), 657–666.
Jia X, Koenig MA, Nickl R, Zhen G, Thakor NV, Geocadin RG. Early Electrophysiologic Markers Predict Functional Outcome Associated with Temperature Manipulation after Cardiac Arrest in Rats. Critical Care Medicine 2008; 36 (6):1909–16 [Editorials] by Tempelhoff, René MD; Yoder, Jeffrey MD. Monitoring the brain: Lack of tools or lack of will? Critical Care Medicine 2008; 36 (6):1983–1984.
Lewitus D, Vogelstein J, Zhen G, Choi YS, Kohn J, Harshbarger S, Jia X. Designing Tyrosine-derived Polycarbonate Polymers for Biodegradable Regenerative Type Neural Interface Capable of Neural Recording. IEEE Trans Neural Syst Rehabil Eng. 2011 Apr;19(2):204–12.
Ma Y, Hu Y, Valentin N, Geocadin R, Thakor NV, Jia X. Time Jitter of Somatosensory Evoked Potentials in Recovery from Hypoxic-ischemic Brain Injury. Journal of Neuroscience Methods 2011 Oct 15;201(2):355–360.
Madhok J, Wu D, Xiong W, Geocadin RG, Jia X. Hypothermia amplifies somatosensory evoked potentials in uninjured rats. J Neurosurg Anesthesiol. 2012 Jul;24(3):197–202.
Xian L, Wu X, Pang L, Lou M, Rosen C, Qiu T, Crane J, Frassica F, Zhang L, Rodriguez JP, Jia X, Yakar S, Xuan S, Efstratiadis A, Wan M, Cao X. Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells. Nature Medicine 2012 18 (7), 1095–1101.
Zhen G, Wen C, Jia X, Li Y, Crane JL, Mears SC, Askin FB, Frassica FJ, Chang W, Yao J, Carrino JA, Cosgarea A, Artemov D, Chen Q, Zhao Z, Zhou X, Riley L, Sponseller P, Wan M, Lu WW, Cao X. Inhibition of TGF- β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis. Nature Medicine 2013 Jun;19(6):704–12.
Li J, Zhen G, Tsai SY, Jia X. Epidermal Stem Cells in Orthopaedic Regenerative Medicine. International Journal of Molecular Sciences. 2013 May 31;14(6):11626–42.