BME News Highlights

Research Highlights

February 1, 2010

Heart cells display ‘nano sense’ on new lab chip

Leslie Tung, left, and Andre Levchenko, right, both of the Department of Biomedical Engineering, with Deok-Ho Kim, a doctoral student in Levchenko's lab.

BME faculty Andre Levchenko and Les Tung along with colleagues in Korea have found that heart cell and tissue properties can be controlled by varying the nano-scale topography of the scaffolds supporting the cells, a surprising indication that heart cells possess a ‘nano-sense’ capable of responding to minute differences in the natural extracellular matrix in the heart. The researchers developed a chip that mimics the natural scaffolds, resulting in lab-grown heart tissue that more closely resembles the real thing.

Additional Information:

JHU Gazette article




 

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