BME News Highlights
February 1, 2010
Heart cells display ‘nano sense’ on new lab chip
Leslie Tung, left, and Andre Levchenko, right, both of the Department of Biomedical Engineering, with Deok-Ho Kim, a doctoral student in Levchenko's lab.
BME faculty Andre Levchenko and Les Tung along with colleagues in Korea
have found that heart cell and tissue properties can be controlled by
varying the nano-scale topography of the scaffolds supporting the cells, a
surprising indication that heart cells possess a ‘nano-sense’ capable of
responding to minute differences in the natural extracellular matrix in the
heart. The researchers developed a chip that mimics the natural
scaffolds, resulting in lab-grown heart tissue that more closely resembles the real thing.
JHU Gazette article
Posted: February 1, 2010