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Research Paper

December 11, 2014

Natalia Trayanova research: insight into mechanisms of alternans in human atrial fibrillation

In a research paper available today, BME professor Natalia Trayanova, BME grad student Kelly Chang and researcher Jason Bayer reveal insights into the mechanisms of proarrhythmic alternans — electrical signals in the heart that alternate from beat to beat— and the role they play in atrial fibrillation. The study, entitled “Disrupted Calcium Release as a Mechanism for Atrial Alternans Associated with Human Atrial Fibrillation,” was published by PLOS Computational Biology. In this study the researchers use computational models to conduct a detailed examination of the causes and contributors to alternans associated with human atrial fibrillation.